Cell counter is a device used for counting the number of live and/or dead cells in culture. Cell counting is a vital step in many experimental workflows to obtain an accurate count of cells before progressing the research with more downstream analysis mainly on preparing to split the cell, transfection experiment, and molecular analysis involving qPCR.
Hemocytometer cell counter vs automated cell counter.
The common way to perform cell counting is either manually by using a hemocytometer or automatically with an automated cell counter. For over decades, hemocytometers have been used by cell biologists to quantify cells selectively within a size range and are cost-effective. However, manual cell counting is often time-consuming, lacks robustness at low sample concentration, and is human error-prone, especially if the researcher working with a huge number of samples.
On the contrary, automated cell counters have become a desirable choice for many researchers due to their versatility in counting a larger number of cells with higher precision, and less error, hence reliable for downstream analysis. This machine will automatically count cells without human dependence and the result is interpreted by using a computer attached to the machine.
How to use automated cell counter?
The automated cell counter is far easier to operate with minimal skills required. The samples are dispensed into one side of the counting chamber and placed on the cell counter. The automated cell counter then counts the number of cells that pass through the tube using optical or electrical impedance sensors. It is capable to provide a total count of mammalian cells and a live/dead ratio in a single step without bias, thus yielding more accurate and reproducible results.
Corning (Corning® Cell Counter | Automated Cell Counter | Corning) has developed an automated cell counter that performs with an exclusive method for high-precision cell counting and viability. Watch video (Corning® Cell Counter Demo Video - YouTube) to learn more.
The main feature of Corning automated cell counter.
Cost-effective: Works with common reusable glass hemocytometers and no consumables required.
Ultra-high precision: ability to accurately count as small as 4 µm (e.g., PBMC).