Creating in vivo environment for cell growth

The use of permeable support systems for cell culture has proven to be an invaluable tool in the cell biology laboratory.

Cell and tissue culture techniques are becoming increasingly important for basic and applied life science research. The development of new culture vessels and cell attachment substrates is currently being driven by the need to produce an environment that resembles the in vivo state as closely as possible to enable the growth of specialized cell types. Cellular functions such as transport, absorption and secretion can also be studied since cells grown on permeable supports provide convenient, independent access to apical and basolateral plasma membrane domains.

Transwell® cell culture inserts are convenient, sterile, easy-to-use permeable support devices for the study of both anchorage-dependent and anchorage-independent cell lines.

  • Designed to produce a cell culture environment that closely resembles the in vivo state.

  • Allows polarized cells to feed basolaterally and thereby carry out metabolic activities in a more natural fashion.

  • Unique self-centered hanging design prevents medium wicking between the insert and outer well.

  • Permits access to the lower compartment through windows in the insert wall.

  • Suspended design allows for undamaged co-culturing of cells in the lower compartment.

  • Available in a range of pore sizes and different membranes to satisfy diverse experimental requirements.

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